Prof Liam Smeeth

Director

United Kingdom

I am Director of the London School of Hygiene and Tropical Medicine and a professor of clinical epidemiology. I am also a practicing doctor in NHS general practice. During my career I have been supported by fellowships from MRC, NIHR and Wellcome. I was previously a Trustee of the British Heart Foundation and a non-executive director of the Medicines and Healthcare products Regulatory Agency. I am a member of the strategic oversight committee for UK Biobank and an elected Fellow of the Academy of Medical Sciences. I co-chair the BMJ Commission on the Future of the NHS.

Affiliations

Executive Office

Professional Support Services

Teaching

I am involved in a range of teaching activities across LSHTM.

Research

Much of my research was based on making better use of computerised clinical data for research. I co-led the creation of the OpenSafely resource in response to the Covid pandemic and helped lead the creation of the 100 million cohort in Brazil. My broad interests include disease aetiology, drug effects, genetics, health and climate change, and non-communicable diseases in low income settings.

Research Area

Electronic health records

Selected Publications

Mortality from Congenital Zika Syndrome - Nationwide Cohort Study in Brazil.

PAIXAO, ES; Cardim, LL; Costa, MC N; BRICKLEY, EB; De Carvalho-Sauer, RC O; Carmo, EH; Andrade, RF S; Rodrigues, MS; Veiga, RV; Costa, LC; Moore, CA; França, GV A; SMEETH, L; RODRIGUES, LC; Barreto, ML; Teixeira, MG;

2022

The New England journal of medicine

Understanding the pathogenesis of lean non-autoimmune diabetes in an African population with newly diagnosed diabetes.

KIBIRIGE, D; SEKITOLEKO, I; Lumu, W; Jones, AG; Hattersley, AT; SMEETH, L; NYIRENDA, MJ;

2022

Diabetologia

Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform

MATHUR, R; Rentsch, CT; Morton, CE; Hulme, WJ; Schultze, A; MacKenna, B; EGGO, RM; BHASKARAN, K; WONG, AY S; WILLIAMSON, EJ; FORBES, H; WING, K; MCDONALD, HI; Bates, C; Bacon, S; Walker, AJ; Evans, D; Inglesby, P; Mehrkar, A; Curtis, HJ; DeVito, NJ; Croker, R; Drysdale, H; Cockburn, J; Parry, J; ... GOLDACRE, B.

2021

Lancet (London, England)

The effect of statins on muscle symptoms in primary care: the StatinWISE series of 200 N-of-1 RCTs.

HERRETT, E; WILLIAMSON, E; Brack, K; PERKINS, A; Thayne, A; SHAKUR-STILL, H; ROBERTS, I; Prowse, D; BEAUMONT, D; JAMAL, Z; GOLDACRE, B; Van Staa, T; MacDonald, TM; Armitage, J; Moore, M; Hoffman, M; SMEETH, L;

2021

Health technology assessment (Winchester, England)

Factors associated with COVID-19-related death using OpenSAFELY.

WILLIAMSON, EJ; Walker, AJ; BHASKARAN, K; Bacon, S; Bates, C; Morton, CE; Curtis, HJ; Mehrkar, A; Evans, D; Inglesby, P; Cockburn, J; MCDONALD, HI; MacKenna, B; TOMLINSON, L; DOUGLAS, IJ; RENTSCH, CT; MATHUR, R; WONG, AY S; GRIEVE, R; Harrison, D; FORBES, H; SCHULTZE, A; Croker, R; Parry, J; Hester, F; ... GOLDACRE, B.

2020

Nature

Data Resource Profile: Clinical Practice Research Datalink (CPRD).

HERRETT, E; Gallagher, AM; BHASKARAN, K; FORBES, H; MATHUR, R; Van Staa, T; SMEETH, L;

2015

International journal of epidemiology

Risk of myocardial infarction and stroke after acute infection or vaccination.

SMEETH, L; THOMAS, SL; Hall, AJ; Hubbard, R; Farrington, P; Vallance, P;

2004

The New England journal of medicine

MMR vaccination and pervasive developmental disorders: a case-control study.

SMEETH, L; Cook, C; Fombonne, E; Heavey, L; RODRIGUES, LC; SMITH, PG; Hall, AJ;

2004

Lancet

OpenSAFELY: A platform for analysing electronic health records designed for reproducible research.

Nab, L; Schaffer, AL; Hulme, W; DeVito, NJ; Dillingham, I; Wiedemann, M; Andrews, CD; Curtis, H; Fisher, L; Green, A; Massey, J; Walters, CE; Higgins, R; Cunningham, C; Morley, J; Mehrkar, A; Hart, L; Davy, S; Evans, D; Hickman, G; Inglesby, P; Morton, CE; Smith, RM; Ward, T; O'Dwyer, T; ... GOLDACRE, B.

2024

Pharmacoepidemiology and drug safety

Clinical coding of long COVID in primary care 2020-2023 in a cohort of 19 million adults: an OpenSAFELY analysis.

Henderson, AD; Butler-Cole, BF; Tazare, J; TOMLINSON, LA; MARKS, M; JIT, M; BRIGGS, A; Lin, L-Y; CARLILE, O; Bates, C; Parry, J; Bacon, SC; Dillingham, I; Dennison, WA; COSTELLO, RE; Wei, Y; Walker, AJ; Hulme, W; GOLDACRE, B; Mehrkar, A; MacKenna, B; OpenSAFELY Collaborative,; HERRETT, E; EGGO, RM;

2024

EClinicalMedicine

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London School of Hygiene & Tropical Medicine