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Professor Chris Drakeley

Professor of Infection and Immunity

United Kingdom

Tel.
+442079272289
I have 30 years’ experience working on malaria with a specific focus on measuring and defining transmission and identifying methods and approaches to stop it. My research includes (i) exploratory work on factors governing transmission and transmission reservoirs, particularly the importance of adults, asymptomatic parasite carriers and people with very low parasitaemias; and (ii) assessing the impact of drugs on transmission and optimal control approaches for transmission reduction. I have led two large programmes funded by BMGF; firstly elucidating the infectious reservoir of transmission in different endemic settings in Kenya and Burkina Faso senior investigator and secondly evaluating the effect of control measures on the infectious reservoir in Uganda, The Gambia, Ethiopia and Burkina Faso. I have also been a senior investigator on large community randomized control studies evaluating school based interventions, foci targeting and mass drug administration. This has included developed operational and laboratory approaches to best evaluate efficacy. My current activities leading several initiatives aimed at further describing transmission and using surveillance to more effectively assess intervention success. OTher focus areas include better understanding of the transmission of zoonotic malaria P.knowlesi and the development of serological assays for malaria (particularly P.vivax) and other infectious diseases.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Centre for Evaluation
Malaria Centre
Vaccine Centre
Centre on Climate Change and Planetary Health

Research

Malaria - Epidemiology, surveillance and transmission
Diagnostics - serological assays
Research Area
Surveillance
Diagnostics
Disease control
Epidemiology
Immunoepidemiology
Immunology
Disease and Health Conditions
Malaria
Neglected Tropical Diseases (NTDs)
Country
Gambia
Uganda
Burkina Faso
Philippines
Ethiopia
Madagascar
Region
Sub-Saharan Africa (developing only)
Latin America & Caribbean (developing only)
East Asia & Pacific (developing only)

Selected Publications

Asymptomatic school children and adults are important for the human infectious reservoir for Plasmodium falciparum malaria in an area of low endemicity in The Gambia
Soumare, HM; Blanken, SL; Ahmad, A; Ooko, M; Gaye, PM; Jadama, L; Camara, MM; Jawara, EA; Lanke, K; Njie, AK; Mendy, M; Etoketim, B; Camara, L; NDIATH, MO; Conteh, B; Muhammed, N; SOREMEKUN, S; Nyassi, A; ERHART, A; DRAKELEY, C; Bousema, T; D'ALESSANDRO, U; Moreno, M;
2025
Journal of Infection
Self-reported COVID-19 severity among persons with tuberculosis infection in western Kenya, 2021
Barsosio, HC; Tangara, B; Ongalo, J; Achieng, M; MARLAIS, T; McCarthy, KD; Otieno, K; Wanjiku, M; MATTHEWMAN, J; Allen, D; Hannan, L; Date, A; Lesosky, M; Kariuki, S; Samuels, AM; DRAKELEY, C; Ter Kuile, FO; Samandari, T;
2025
PLOS global public health
Guidance for conducting and evaluating serological surveys to assess interruption of yaws transmission in the context of an eradication target.
Mitjà, O; Gass, K; MARKS, M; Cooper, PJ; Diggle, PJ; Waller, L; Agana-Nsiire, P; Dofitas, BL; Dyson, L; Jacobson, J; Kaldor, J; Kim, SH; Vaz Nery, S; Revankar, C; Sopoh, G; Solomon, AW; Dagne, DA; Pathak, P; Yajima, A; Lin, Z; Barogui, MY T; Scholte, RC; Sanikullah, KH; DRAKELEY, C; Stresman, G; ... Asiedu, KB.
2025
PLoS neglected tropical diseases
Safety and efficacy of single-dose primaquine to interrupt Plasmodium falciparum malaria transmission in children compared with adults: a systematic review and individual patient data meta-analysis
Yilma, D; Stepniewska, K; Bousema, T; DRAKELEY, C; Eachempati, P; Guerin, PJ; Mårtensson, A; Mwaiswelo, R; Taylor, WR; Barnes, KI; Allen, EN; Arango, E; Barnes, KI; Bastiaens, GJ H; Bousema, T; Brown, J; Chhajed, R; Commons, RJ; D'Alessandro, U; Day, NP J; Dhorda, M; Dicko, A; Dondorp, A; Drakeley, C; Dysoley, L; ... Yilma, D.
2025
The Lancet infectious diseases
Preferential transmission of minority and drug-resistant clones in polyclonal infections in Mali.
VANHEER, LN; Manko, E; Mahamar, A; PHELAN, J; Sanogo, K; Sinaba, Y; Niambele, SM; Sacko, A; Keita, S; Youssouf, A; Diallo, M; Soumare, HM; Lanke, K; Issiaka, D; Diawara, H; Traore, SF; Grignard, L; Dicko, A; DRAKELEY, C; CAMPINO, S; STONE, W;
2025
Malaria journal
Household costs associated with zoonotic Plasmodium knowlesi, P. falciparum, P. vivax and P. malariae infections in Sabah, Malaysia.
Abraham, P; McMullin, C; William, T; Rajahram, GS; Jelip, J; Teo, R; DRAKELEY, C; Manah, AM; Anstey, NM; Grigg, MJ; Devine, A;
2025
PLoS neglected tropical diseases
Dataset for the article: Self-reported COVID-19 severity among persons with tuberculosis infection in western Kenya, 2021
Barsosio, HC; Tangara, B; Ongalo, J; Achieng, M; MARLAIS, T; McCarthy, KD; Otieno, K; Wanjiku, M; MATTHEWMAN, J; Allen, D; Hannan, L; Date, A; Lesosky, M; Kariuki, S; Samuels, AM; DRAKELEY, C; Ter Kuile, F; Samandari, T;
2025
Liverpool School of Tropical Medicine
Genomic epidemiology of Plasmodium knowlesi reveals putative genetic drivers of adaptation in Malaysia.
Westaway, JA F; Diez Benavente, E; Auburn, S; Kucharski, M; Aranciaga, N; Nayak, S; William, T; Rajahram, GS; Piera, KA; Braima, K; Tan, AF; Alaza, DA; Barber, BE; DRAKELEY, C; Amato, R; Sutanto, E; Trimarsanto, H; Jelip, J; Anstey, NM; Bozdech, Z; Field, M; Grigg, MJ;
2025
PLoS neglected tropical diseases
New insights on malaria parasite adaptation yielded by samples archived for more than 50 years
AMAMBUA-NGWA, A; Diop, MF; DRAKELEY, C; D’Alessandro, U; Kwiatkowski, D; CONWAY, D;
2025
bioRxiv
Life cycle assessment of a clinical malaria trial in Mali reveals large environmental impacts of electricity consumption and international travel
Smit, MJ; Mahamar, A; Kooistra, E; Lanke, K; Sanogo, K; Okedy, PW; Yehia, MA; DRAKELEY, C; Touw, H; STONE, W; Dicko, A; Bousema, T; Stobernack, T;
2025
PLOS Sustainability and Transformation
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