Prof Alison Elliott

Professor of Tropical Medicine

United Kingdom

Tel.

+44 207 927 2116

Email
Alison

Alison Elliott is theme leader for Vaccines and Immunity and head of the Immunomodulation and Vaccines research programme at the MRC/Uganda Virus Research Institute (UVRI) and LSHTM Uganda Research Unit. She is also director of the Makerere University – UVRI Centre of Excellence for Infection and Immunity Research and Training, and Professor of Tropical Medicine at the London School of Hygiene & Tropical Medicine.

Affiliations

Department of Clinical Research

Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre

TB Centre

Vaccine Centre

Research

She became interested in parasitology and research in Africa as an undergraduate and this interest was encouraged further by an elective in The Gambia. After completing medical training she joined the London School of Hygiene & Tropical Medicine and, during the late ‘80s and early ‘90s, undertook studies on the interaction between tuberculosis and HIV infection in Zambia. An infectious diseases fellowship in Denver, Colorado, followed, providing an opportunity to learn about management of drug resistant tuberculosis and about laboratory immunology. This enabled her to plan and conduct subsequent clinical-immuno-epidemiological studies. Since 1997 she has been based in Uganda at the MRC/UVRI and LSHTM Uganda Unit. Current interests focus on the effects of chronic, immunomodulating infections (such as helminth infections) on immune responses to vaccines and on infectious and allergic disease incidence in children in Uganda; and on research capacity building in Africa.

Research Area

Clinical trials

Global Health

Helminths

Immunisation

Parasites

Vaccines

Vector control

Immunoepidemiology

Disease and Health Conditions

Allergy

HIV/AIDS

Neglected Tropical Diseases (NTDs)

Schistosomiasis

Tropical diseases

Tuberculosis

Infectious diseases

Vector borne diseases

Country

Uganda

Zambia

Region

Sub-Saharan Africa (developing only)

Selected Publications

High-Dose Oral and Intravenous Rifampicin for the Treatment of Tuberculous Meningitis in Predominantly Human Immunodeficiency Virus (HIV)-Positive Ugandan Adults: A Phase II Open-Label Randomized Controlled Trial.

CRESSWELL, FV; Meya, DB; Kagimu, E; GRINT, D; Te Brake, L; Kasibante, J; Martyn, E; Rutakingirwa, M; Quinn, CM; Okirwoth, M; Tugume, L; Ssembambulidde, K; Musubire, AK; Bangdiwala, AS; Buzibye, A; Muzoora, C; Svensson, EM; Aarnoutse, R; Boulware, DR; ELLIOTT, AM;

2021

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Immunological Considerations for Schistosoma Vaccine Development: Transitioning to Endemic Settings.

Driciru, E; Koopman, JP R; COSE, S; Siddiqui, AA; Yazdanbakhsh, M; ELLIOTT, AM; Roestenberg, M;

2021

Frontiers in immunology

Malaria is a cause of iron deficiency in African children.

Muriuki, JM; Mentzer, AJ; Mitchell, R; WEBB, EL; Etyang, AO; Kyobutungi, C; Morovat, A; Kimita, W; Ndungu, FM; Macharia, AW; Ngetsa, CJ; Makale, J; Lule, SA; Musani, SK; Raffield, LM; Cutland, CL; Sirima, SB; Diarra, A; Tiono, AB; Fried, M; Gwamaka, M; Adu-Afarwuah, S; Wirth, JP; Wegmüller, R; Madhi, SA; ... Atkinson, SH.

2021

Nature medicine

BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial.

PRENTICE, S; Nassanga, B; WEBB, EL; Akello, F; Kiwudhu, F; Akurut, H; ELLIOTT, AM; Arts, RJ W; Netea, MG; DOCKRELL, HM; COSE, S; Delayed BCG Study Team,;

2021

The Lancet. Infectious diseases

Population differences in vaccine responses (POPVAC): scientific rationale and cross-cutting analyses for three linked, randomised controlled trials assessing the role, reversibility and mediators of immunomodulation by chronic infections in the tropics.

NKURUNUNGI, G; ZIRIMENYA, L; NATUKUNDA, A; Nassuuna, J; Oduru, G; Ninsiima, C; Zziwa, C; Akello, F; Kizindo, R; Akello, M; KALEEBU, P; WAJJA, A; Luzze, H; COSE, S; WEBB, E; ELLIOTT, AM; POPVAC trial team,;

2021

BMJ open

Cross-reactive carbohydrate determinant-specific IgE obscures true atopy and exhibits ⍺-1,3-fucose epitope-specific inverse associations with asthma.

NKURUNUNGI, G; MPAIRWE, H; Versteeg, SA; Van Diepen, A; Nassuuna, J; Kabagenyi, J; Nambuya, I; Sanya, RE; Nampijja, M; Serna, S; Reichardt, N-C; Hokke, CH; WEBB, EL; Van Ree, R; Yazdanbakhsh, M; ELLIOTT, AM;

2020

ALLERGY

Maternal Latent Mycobacterium tuberculosis Does Not Affect the Infant Immune Response Following BCG at Birth: An Observational Longitudinal Study in Uganda.

Lubyayi, L; Mawa, PA; Nabakooza, G; Nakibuule, M; Tushabe, JV; Serubanja, J; Aibo, D; Akurut, H; Tumusiime, J; Hasso-Agopsowicz, M; KALEEBU, P; Levin, J; DOCKRELL, HM; Smith, S; WEBB, EL; ELLIOTT, AM; COSE, S;

2020

FRONTIERS IN IMMUNOLOGY

Structural and social factors affecting COVID-19 vaccine uptake among healthcare workers and older people in Uganda: A qualitative analysis. Data file

Sliversteri, S; SSALI, A; BAHEMUKA, UM; Nsubuga, D; Muwanga, M; Nsereko, C; Ssemwanga, E; Robert, A; SEELEY, J; ELLIOTT, A; Ruzagira, E;

2024

PLOS Global Public Health

Structural and social factors affecting COVID-19 vaccine uptake among healthcare workers and older people in Uganda: A qualitative analysis.

Slivesteri, S; SSALI, A; BAHEMUKA, UM; Nsubuga, D; Muwanga, M; Nsereko, C; Ssemwanga, E; Robert, A; SEELEY, J; ELLIOTT, A; RUZAGIRA, E;

2024

PLOS Glob Public Health

Data supporting “The effect of current helminth infection on vaccine responses among adolescents living in helminth-endemic islands of Lake Victoria, Uganda”

Natukunda, A; ZIRIMENYA, L; NKURUNUNGI, G; Nassuna, J; ELLIOTT, AM; WEBB, E;