I am an Assistant Professor in the TB Modelling Group at LSHTM. I am also a member of the Centre for Mathematical Modelling of Infectious Diseases and the TB Centre. My work focusses on the use of mathematical models to study the epidemiology and control of tuberculosis.
I originally studied Physics and obtained a PhD in Computational Biology from University College London. Prior to joining LSHTM I worked at the Pirbright Institute developing mathematical models to study the spread and control of vector-borne livestock diseases.
I originally studied Physics and obtained a PhD in Computational Biology from University College London. Prior to joining LSHTM I worked at the Pirbright Institute developing mathematical models to study the spread and control of vector-borne livestock diseases.
Affiliations
Department of Infectious Disease Epidemiology and Dynamics
Faculty of Epidemiology and Population Health
Centres
Centre for Mathematical Modelling of Infectious Diseases
TB Centre
Teaching
I am a module organiser and tutor for the distance learning MSc module Modelling and the Dynamics of Infectious Diseases (EPM302). I also teach on the in house MSc programme and the LSHTM Infectious Disease Modelling summer short course.
Research
My research uses mathematical models to study a range of questions about the natural history and control of tuberculosis (TB). My current projects include:
Mathematical modelling of the impact and cost-effectiveness of novel TB vaccines
Macro-economic analysis of the cost of TB in India
Evaluation of the impact of community based TB screening strategies in South Africa, Zambia, Zimbabwe and Mozambique (XACTIII)
Mathematical modelling of the impact and cost-effectiveness of novel TB vaccines
Macro-economic analysis of the cost of TB in India
Evaluation of the impact of community based TB screening strategies in South Africa, Zambia, Zimbabwe and Mozambique (XACTIII)
Research Area
Mathematical modelling
Vaccines
Health economics
Epidemiology
Disease and Health Conditions
Tuberculosis
HIV/AIDS
Selected Publications
Variance-based sensitivity analysis of tuberculosis transmission models.
2022
Journal of the Royal Society, Interface
Modelling the impact of tuberculosis preventive therapy: the importance of disease progression assumptions
2019
BMC infectious diseases
Estimating the Impact of Tuberculosis Case Detection in Constrained Health Systems: An Example of Case-Finding in South Africa.
2019
American Journal of Epidemiology
Quantifying the roles of host movement and vector dispersal in the transmission of vector-borne diseases of livestock.
2017
PLOS COMPUTATIONAL BIOLOGY
Ability of preventive therapy to cure latent Mycobacterium tuberculosis infection in HIV-infected individuals in high-burden settings.
2014
Proceedings of the National Academy of Sciences of the United States of America