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Dr Joe Biggs

Research Fellow in Epidemiology

United Kingdom

Jump to: Affiliations Teaching Research Publications
I am a Research Fellow in Epidemiology working on vector-borne diseases and a member of the International Statistics and Epidemiology Group (ISEG). My research focuses predominantly on improving the surveillance and control of malaria, dengue and Zika. This mainly involves characterising the heterogeneity of disease transmission to optimise the deployment of limited control interventions and design of large-scale cluster randomised control trials. My work relies on the close collaborations I have with research groups across the world with capacity sharing being a major focus. I have been a member of the school since 2016, with one year based in Tanzania, and completed my PhD in dengue immunoepidemiology in 2021.

Affiliations
Department of Infectious Disease Epidemiology and International Health
Faculty of Epidemiology and Population Health

Centres

Malaria Centre

Teaching
I lecture on immunoepidemiology for the Advanced Immunology 2 MSc module. I run practical sessions for both the Basic Epidemiology MSc module and the Introductory Course in Epidemiology and Medical Statistics (ICEM) short course. I have supervised seven MSc students conducting their summer projects.

Research
My main research concerns the heterogeneity of vector-borne disease transmission dynamics. My previous work involved conducting epidemiological analyses on large-scale malaria and dengue seroprevalence surveys in South Africa, Tanzania, Equatorial Guinea and the Philippines. This resulted in the identification of hotspots of disease transmission and the development of novel surveillance strategies. My current research, funded by the Gates foundation, focuses on characterising the heterogeneity of disease outcomes in large cluster randomised control trials. This work is to help ensure future trials are adequately powered to detect the impacts of novel interventions that are vital for combatting malaria and other vector-borne diseases.
Research Area
Epidemiology
Statistical methods
Diagnostics
Immunoepidemiology
Vector control
Surveillance
Randomised controlled trials
Medical entomology
Disease and Health Conditions
Malaria
Dengue
Zika
Vector borne diseases
Country
South Africa
Tanzania
Cote d'Ivoire
Equatorial Guinea
Vietnam
Philippines

Selected Publications
Combining rapid diagnostic tests to estimate primary and post-primary dengue immune status at the point of care.
BIGGS, JR; Sy, AK; Ashall, J; Santoso, MS; BRADY, OJ; Reyes, MA J; Quinones, MA; JONES-WARNER, W; Tandoc, AO; Sucaldito, NL; Mai, HK; Lien, LT; Thai, HD; Nguyen, HA T; Anh, DD; Iwasaki, C; KITAMURA, N; Van Loock, M; Herrera-Taracena, G; Menten, J; Rasschaert, F; Van Wesenbeeck, L; Masyeni, S; Haryanto, S; Yohan, B; ... HIBBERD, ML.
2022
PLoS Neglected Tropical Diseases
Estimating the annual dengue force of infection from the age of reporting primary infections across urban centres in endemic countries.
BIGGS, JR; Sy, AK; SHERRATT, K; BRADY, OJ; KUCHARSKI, AJ; FUNK, S; Reyes, MA J; Quinones, MA; JONES-WARNER, W; Avelino, FL; Sucaldito, NL; Tandoc, AO; La Paz, EC-D; Capeding, MR Z; Padilla, CD; HAFALLA, JC R; HIBBERD, ML;
2021
BMC medicine
Serological Evidence of Widespread Zika Transmission across the Philippines.
BIGGS, JR; Sy, AK; BRADY, OJ; KUCHARSKI, AJ; FUNK, S; Tu, Y-H; Reyes, MA J; Quinones, MA; JONES-WARNER, W; Ashall, J; Avelino, FL; Sucaldito, NL; Tandoc, AO; Cutiongco-de la Paz, E; Capeding, MR Z; Padilla, CD; HIBBERD, ML; HAFALLA, JC R;
2021
Viruses
Effectiveness and cost-effectiveness of reactive, targeted indoor residual spraying for malaria control in low-transmission settings: a cluster-randomised, non-inferiority trial in South Africa.
BATH, D; COOK, J; Govere, J; Mathebula, P; Morris, N; Hlongwana, K; Raman, J; Seocharan, I; Zitha, A; Zitha, M; Mabuza, A; Mbokazi, F; Machaba, E; Mabunda, E; Jamesboy, E; BIGGS, J; DRAKELEY, C; Moonasar, D; Maharaj, R; Coetzee, M; PITT, C; KLEINSCHMIDT, I;
2021
Lancet
A serological framework to investigate acute primary and post-primary dengue cases reporting across the Philippines.
BIGGS, JR; Sy, AK; BRADY, OJ; KUCHARSKI, AJ; FUNK, S; Reyes, MA J; Quinones, MA; JONES-WARNER, W; Tu, Y-H; Avelino, FL; Sucaldito, NL; Mai, HK; Lien, LT; Do Thai, H; Nguyen, HA T; Anh, DD; Iwasaki, C; KITAMURA, N; Yoshida, L-M; Tandoc, AO; La Paz, EC-D; Capeding, MR Z; Padilla, CD; HAFALLA, JC R; HIBBERD, ML;
2020
BMC medicine
Serology reveals heterogeneity of Plasmodium falciparum transmission in northeastern South Africa: implications for malaria elimination.
BIGGS, J; Raman, J; COOK, J; Hlongwana, K; DRAKELEY, C; Morris, N; Serocharan, I; Agubuzo, E; Kruger, P; Mabuza, A; Zitha, A; Machaba, E; Coetzee, M; KLEINSCHMIDT, I;
2017
Malaria journal
A systematic review of sample size estimation accuracy on power in malaria cluster randomised trials measuring epidemiological outcomes.
BIGGS, J; Challenger, JD; Hellewell, J; Churcher, TS; COOK, J;
2024
BMC medical research methodology
Could prophylactic antivirals reduce dengue incidence in a high-prevalence endemic area?
Jafari, Y; BRADY, OJ; BIGGS, JR; Lien, LT; Mai, HK; Nguyen, HA T; Van Loock, M; Herrera-Taracena, G; Menten, J; Iwasaki, C; Takegata, M; Kitamura, N; Do Thai, H; Minh, BX; Morita, K; Anh, DD; Clifford, S; PREM, K; Hafalla, J; EDMUNDS, WJ; Yoshida, LM; HIBBERD, ML; Hué, S;
2024
PLoS neglected tropical diseases
A phylogenetic study of dengue virus in urban Vietnam shows long-term persistence of endemic strains.
Ashall, J; SHAH, S; BIGGS, JR; Chang, J-NR; Jafari, Y; BRADY, OJ; Mai, HK; Lien, LT; Do Thai, H; Nguyen, HA T; Anh, DD; Iwasaki, C; Kitamura, N; Van Loock, M; Herrera-Taracena, G; Rasschaert, F; Van Wesenbeeck, L; Yoshida, L-M; HAFALLA, JC R; HUE, S; HIBBERD, ML;
2023
Virus evolution
Immuno-epidemiological analysis of dengue to enhance surveillance.
BIGGS, JR;
2022
London School of Hygiene & Tropical Medicine
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Joe Biggs

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United Kingdom