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Dr Rachael Burke

Clinical Assistant Professor in Training

United Kingdom

I am an NIHR Assistant Professor, combing NHS work as an Infectious Disease and General (Internal) Medicine specialist registrar with work as an academic at the school.  I work on clinical epidemiology related to TB and HIV. 

 

I previously lived and worked in Malawi (when doing my Wellcome-funded clinical PhD), but am now London-based.  I work closely with Prof Peter MacPherson (now at Glasgow University) and Prof Liz Corbett (at the school), among others.  I am member of the LSHTM TB Centre.

 

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Teaching

I am the co-module organiser (with Prof Liz Corbett) on the TB module in the MSc Infectious Disease.

Research

I have worked on community, primary care and hospital level studies: including TB Active Case Finding and diagnostic studies, but I have a particular interest in Advanced HIV Disease and reducing mortality among people living with HIV admitted to hospital. 

 

I was PI of the CASTLE trial about enhanced TB diagnostics (Computer Aided Diagnosis chest X-ray and urine LAM testing), and am co-PI of the SaDAPT trial (Same Day ART in Presumptive TB) with colleagues in Lesotho, Malawi and Switzerland.

 

I also experience doing various systematic reviews related to TB and HIV, and being an expert contributor to several WHO guideline develop processes.

Selected Publications

Impact of active case finding for tuberculosis with mass chest X-ray screening in Glasgow, Scotland, 1950-1963: an epidemiological analysis of historical data
MacPherson, P; Stagg, H; SCHWALB, A; Henderson, H; Taylor, A; BURKE, R; RICKMAN, H; Miller, C; HOUBEN, RM G J; Dodd, P; CORBETT, E;
2024
medRxiv
Impact of active case finding for tuberculosis with mass chest X-ray screening in Glasgow, Scotland, 1950-1963: An epidemiological analysis of historical data.
MacPherson, P; Stagg, HR; SCHWALB, A; Henderson, H; Taylor, AE; BURKE, RM; RICKMAN, HM; Miller, C; HOUBEN, RM G J; Dodd, PJ; CORBETT, EL;
2024
PLoS Medicine
Summary of posterior draws from pulmonary tuberculosis model
MacPherson, P; Stagg, HR; SCHWALB, A; Henderson, H; Taylor, AE; BURKE, RM; RICKMAN, HM; Miller, C; HOUBEN, RM G J; Dodd, PJ; CORBETT, EL;
2024
PLOS Medicine
HIV hospitalisation systematic review data
BURKE, R;
2024
London School of Hygiene & Tropical Medicine
Impact of active case finding for tuberculosis with mass chest X-ray screening in Glasgow, Scotland, 1950-1963: an epidemiological analysis of historical data
MacPherson, P; Stagg, H; SCHWALB, A; Henderson, H; Taylor, A; BURKE, R; RICKMAN, H; Miller, C; HOUBEN, RM G J; Dodd, P; CORBETT, E;
2024
medRxiv
Treatment preferences among people at risk of developing tuberculosis: A discrete choice experiment.
Kamchedzera, W; Quaife, M; Msukwa-Panje, W; BURKE, RM; Macpherson, L; Kumwenda, M; Twabi, HH; Quartagno, M; MacPherson, P; Esmail, H;
2024
PLOS global public health
Distribution and transmission of<i>M. tuberculosis</i>in a high-HIV prevalence city in Malawi: a genomic and spatial analysis
Chitwood, M; Corbett, E; Ndhlovu, V; Sobkowiak, B; Colijn, C; Andrews, J; BURKE, R; Cudahy, PG T; Dodd, P; Imai-Eaton, J; Engelthaler, D; Folkerts, M; Feasey, H; Lan, Y; Lewis, J; Menzies, N; Chipungu, G; Nliwasa, M; Weinberger, D; Warren, J; Salomon, J; MacPherson, P; Cohen, T;
2024
medRxiv
Enhanced tuberculosis diagnosis with computer-aided chest X-ray and urine LAM in adults with HIV admitted to hospital (CASTLE study): A cluster randomised trial.
BURKE, RM; Nyirenda, SK; Mtenga, T; Twabi, HH; Joekes, E; Walker, NF; Nyirenda, R; Gupta-Wright, A; Nliwasa, M; FIELDING, K; MacPherson, P; CORBETT, EL;
2024
Clinical Infectious Diseases
Reasons for disengagement from antiretroviral care in the era of "Treat All" in low- or middle-income countries: a systematic review.
BURKE, RM; RICKMAN, HM; Pinto, C; Ehrenkranz, P; Choko, A; Ford, N;
2024
Journal of the International AIDS Society
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