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Dr Rachael Burke

Clinical Assistant Professor in Training

United Kingdom

I am an Infectious Disease and General (Internal) Medicine registrar. I completed a post as a Wellcome Trust Clinical PhD fellow based in Malawi with the Malawi Liverpool Wellcome Clinical Research Programme in 2023. My research interests are in tuberculosis and HIV co-infection, improving infectious disease diagnostics and in reducing in-hospital mortality for people living with HIV in low income settings. I am currently a distance learning tutor on the MSc in Infectious Diseases, and am delighted to be returning to the school as an NIHR Clinical Lecturer in 2024.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Teaching

I am a tutor on the LSHTM Distance Learning MSc in Infectious Diseases, contributing to the TB module.

Selected Publications

Distribution and transmission of<i>M. tuberculosis</i>in a high-HIV prevalence city in Malawi: a genomic and spatial analysis
Chitwood, MH; Corbett, EL; Ndhlovu, V; Sobkowiak, B; Colijn, C; Andrews, JR; BURKE, RM; Cudahy, PG T; Dodd, PJ; Imai-Eaton, JW; Engelthaler, DM; Folkerts, M; Feasey, H; Lan, Y; Lewis, J; Menzies, NA; Chipungu, G; Nliwasa, M; Weinberger, DM; Warren, JL; Salomon, JA; MacPherson, P; Cohen, T;
2024
Cold Spring Harbor Laboratory
Enhanced tuberculosis diagnosis with computer-aided chest X-ray and urine LAM in adults with HIV admitted to hospital (CASTLE study): A cluster randomised trial.
BURKE, RM; Nyirenda, SK; Mtenga, T; Twabi, HH; Joekes, E; Walker, NF; Nyirenda, R; Gupta-Wright, A; Nliwasa, M; FIELDING, K; MacPherson, P; Corbett, EL;
2024
Clinical Infectious Diseases
Reasons for disengagement from antiretroviral care in the era of "Treat All" in low- or middle-income countries: a systematic review.
BURKE, RM; Rickman, HM; Pinto, C; Ehrenkranz, P; Choko, A; Ford, N;
2024
Journal of the International AIDS Society
Same-day versus rapid ART initiation in HIV-positive individuals presenting with symptoms of tuberculosis: Protocol for an open-label randomized non-inferiority trial in Lesotho and Malawi.
Gerber, F; Semphere, R; Lukau, B; Mahlatsi, P; Mtenga, T; Lee, T; Kohler, M; Glass, TR; Amstutz, A; Molatelle, M; MacPherson, P; Marake, NB; Nliwasa, M; Ayakaka, I; BURKE, R; Labhardt, N;
2024
PloS one
Community-level variation in TB testing history in Blantyre, Malawi.
NIGHTINGALE, ES; Feasey, HR A; Khundi, M; Soko, RN; BURKE, RM; Nliwasa, M; Twabi, H; Mpunga, JA; FIELDING, K; MacPherson, P; CORBETT, EL;
2024
The international journal of tuberculosis and lung disease
Prevalence of bacteriologically-confirmed pulmonary tuberculosis in urban Blantyre, Malawi 2019-20: Substantial decline compared to 2013-14 national survey.
Feasey, HR A; Khundi, M; Nzawa Soko, R; NIGHTINGALE, E; BURKE, RM; Henrion, MY R; Phiri, MD; BURCHETT, HE; Chiume, L; Nliwasa, M; Twabi, HH; Mpunga, JA; MacPherson, P; CORBETT, EL;
2023
PLOS global public health
Accuracy of upper respiratory tract samples to diagnose Mycobacterium tuberculosis: a systematic review and meta-analysis.
Savage, HR; Rickman, HM; BURKE, RM; Odland, ML; Savio, M; Ringwald, B; Cuevas, LE; MacPherson, P;
2023
The Lancet. Microbe
Ending AIDS deaths requires improvements in clinical care for people with advanced HIV disease who are seriously ill.
BURKE, RM; Feasey, N; Rangaraj, A; Camps, MR; Meintjes, G; El-Sadr, WM; Ford, N;
2023
The lancet. HIV
Community-level variation in TB testing history: analysis of a prevalence survey in Blantyre, Malawi
NIGHTINGALE, E; Feasey, H; Khundi, M; Soko, RN; BURKE, R; Nliwasa, M; Twabi, H; Mpunga, J; FIELDING, K; MacPherson, P; Corbett, E;
2023
medRxiv
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