I have worked at the London School of Hygiene and Tropical Medicine (LSHTM) since February 2013. Initially, I worked as a Data Manager within the Clinical Trials Unit (CTU), before completing an MSc in Medical Statistics at LSHTM and starting a new role as a Research Fellow in Medical Statistics. This role involves providing data management and statistical support for several randomised controlled trials overseen by the LSHTM CTU. I am also currently undertaking a part-time PhD assessing the performance of statistical methods for handling non-adherence to interventions in randomised non-inferiority trials.
Affiliations
Department of Medical Statistics
Faculty of Epidemiology and Population Health
Teaching
I am co-module organiser for the face-to-face Clinical Trials module (2033) and teach predominantly on this course. I also tutor on the Regression module for the MSc in Medical Statistics and assist with the distance learning module Basic Statistics for Clinical Trials (CTM102).
Research
I am currently providing statistical support for the following randomised controlled trials:
AIMS (investigating the effect of Irbesartan on aortic dilatation in Marfan syndrome)
ARREST (investigating the effect of expedited transfer to a cardiac arrest centre for non-ST elevation out-of-hospital cardiac arrest; arrest.lshtm.ac.uk)
BHF PROTECT-TAVI (investigating the effect of a cerebral embolic protection device in participants with aortic valve stenosis planned for treatment by transcatheter aortic valve implantation)
CHIP-BCIS3 (investigating the effect of a strategy of percutaneous left ventricular unloading in patients undergoing high-risk percutaneous coronary intervention (PCI))
ERIC-PPCI (investigating the effect of remote ischaemic conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing primary PCI; ericppci.lshtm.ac.uk)
PREVENTT (investigating the effect of intravenous iron in patients with anaemia undergoing major open abdominal surgery; preventt.lshtm.ac.uk)
REVIVED-BCIS2 (investigating the effect of PCI compared to optimal medical therapy alone for ischaemic left ventricular dysfunction; revived.lshtm.ac.uk)
TB Practecal (evaluating regimens containing Bedaquiline and Pretomanid for the treatment of adult patients with pulmonary multidrug resistant tuberculosis; msf.org.uk/tb-practecal)
AIMS (investigating the effect of Irbesartan on aortic dilatation in Marfan syndrome)
ARREST (investigating the effect of expedited transfer to a cardiac arrest centre for non-ST elevation out-of-hospital cardiac arrest; arrest.lshtm.ac.uk)
BHF PROTECT-TAVI (investigating the effect of a cerebral embolic protection device in participants with aortic valve stenosis planned for treatment by transcatheter aortic valve implantation)
CHIP-BCIS3 (investigating the effect of a strategy of percutaneous left ventricular unloading in patients undergoing high-risk percutaneous coronary intervention (PCI))
ERIC-PPCI (investigating the effect of remote ischaemic conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing primary PCI; ericppci.lshtm.ac.uk)
PREVENTT (investigating the effect of intravenous iron in patients with anaemia undergoing major open abdominal surgery; preventt.lshtm.ac.uk)
REVIVED-BCIS2 (investigating the effect of PCI compared to optimal medical therapy alone for ischaemic left ventricular dysfunction; revived.lshtm.ac.uk)
TB Practecal (evaluating regimens containing Bedaquiline and Pretomanid for the treatment of adult patients with pulmonary multidrug resistant tuberculosis; msf.org.uk/tb-practecal)
Selected Publications
Prognostic impact of inducible ischaemia in ischaemic left ventricular dysfunction: the REVIVED-BCIS2 trial.
2024
European heart journal
How much should we still worry about QTc prolongation in rifampicin-resistant tuberculosis? ECG findings from TB-PRACTECAL clinical trial.
2024
Antimicrobial agents and chemotherapy
Impact of Anatomical and Viability-Guided Completeness of Revascularization on Clinical Outcomes in Ischemic Cardiomyopathy.
2024
Journal of the American College of Cardiology
Percutaneous Left Ventricular Unloading During High-Risk Coronary Intervention: Rationale and Design of the CHIP-BCIS3 Randomized Controlled Trial.
2024
Circulation. Cardiovascular interventions
Percutaneous Revascularisation for Ischemic Left Ventricular Dysfunction: Cost-Effectiveness Analysis of the REVIVED-BCIS2 Trial.
2023
Circulation. Cardiovascular quality and outcomes
Assessing the efficacy of tuberculosis regimens in the presence of treatment non-adherence
2023
Union World Conference on Lung Health