I am an epidemiologist, currently funded by GlaxoSmithKline. I initially studied physiology at BSc and PhD level in Manchester. Since then, I spent several years at the UK Medicines & Healthcare Products Regulatory Agency and in the pharmaceutical industry investigating adverse effects of drugs - both in clinical trials and post-marketing. I completed the MSc in epidemiology at LSHTM in 2005.
Affiliations
Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health
Centres
Centre for Data and Statistical Science for Health
Teaching
Most of my teaching is split between the LSHTM pharmacoepidemiology range of short courses and the MSc in Epidemiology,
Research
I am interested in pharmacoepidemiology, and in particular, how large electronic health record databases can be used to investigate the effects of drugs - both harmful and beneficial. I am exploring methodologies to minimize some of the biases inherent in the research of drug effects, and my main current areas of interest include case-only approaches to study design, the use of non-interventional data to estimate intended treatment effects, quantitative bias analysis, and the application of high dimensional propensity scores in electronic health data.
Selected Publications
Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK.
2018
The lancet. Diabetes & endocrinology
Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015.
2017
BMJ (Clinical research ed)
Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs.
2012
BMJ (Clinical research ed)
