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Miss Victoria Miari

Principal Scientific Officer

United Kingdom

I am a trained and HCPC registered Clinical Scientist in Microbiology, with a specialist interest in Sexually Transmitted Infections. I've been involved in various research studies including HSV, syphilis and gonorrhoea. A particular interest of mine is antimicrobial resistance in STIs and specifically Neisseria gonorrhoeae. I received a B.Sc. (Hons) in Infectious Diseases from the University of East London and subsequently gained an M.Sc. in Clinical Microbiology by Queen Mary University of London and Pg.Dip. in Sexual Health by Glasgow Caledonian University. I was accepted in the competitive clinical scientist training programme with the British National Health Service and as part of this, sat the FRCPath Part 1 examination in Clinical Microbiology. 

I am actively involved in the shortlisting and assessments for the NHS Scientist Training Programme and I am part of the London Training Consortium for STP Trainees.

Affiliations

Faculty of Infectious and Tropical Diseases

Centres

Antimicrobial Resistance Centre

Teaching

Teaching
MSc Programmes:

Medical Microbiology
Control of Infectious Diseases

MSc Modules:

Core Bacteriology & Virology
Diagnostic Bacteriology (co-MO)
Clinical Virology (co-MO)
Mycology (co-DMO)

I lead the Core Bacteriology, Core Virology and Clinical Virology practical teaching for the MSc in Medical Microbiology and support practical classes for Diagnostic Bacteriology and Mycology modules. I also deliver lectures in the Core Bacteriology, Diagnostic Bacteriology and Introduction to Disease Agents and Their Control modules. I regularly supervise MSc project students.

2013-2014: Multi-site Neisseria gonorrhoeae infection and antimicrobial resistance
2014-2015: Optimisation of broth culture for Neisseria gonorrhoeae and gene transfer from commensal Neisseria species
2016-2017: Understanding the mechanism of resistance for the novel antimicrobial closthioamide in Neisseria gonorrhoeae
2018-2019: Antimicrobial susceptibility of N. gonorrhoeae strains to chlorhexidine by agar dilution and microbroth dilution method
2018-2019: Carriage and characterisation of commensal Neisseria species in the human pharynx
2019-2020: Literature Review of Viability PCR within Clinical Microbiology
2019-2020: Systematic Review of gonococcal post-cephalospirin treatment failures
2021-2022: Induction of chlorhexidine resistance in susceptible Neisseria gonorrhoeae strains

Research

Research interests: Clinical diagnostics, Antimicrobial resistance, Sexually Transmitted Infections, Neisseria gonorrhoeae, Pharyngeal gonorrhoea, AMR surveillance, Health Services Research.

My research focuses on antimicrobial resistant gonorrhoea and how pharyngeal infection facilitates development and transmission of AMR. Specifically I am interested in the role of commensal species in the genetic transfer of AMR genes, as well as the evaluation novel treatments for gonorrhoea such as topical antiseptics.

I am evaluating the in vitro efficacy of chlorhexidine against N. gonorrhoeae with the view to implement chlorhexidine containing solutions as gonococcal treatment, thereby improving antimicrobial stewardship.

Research Area
Microbiology
Clinical research
AMR (Antimicrobial resistance)
Antimicrobial agents
Sexual health
Diagnostics
Laboratory diagnosis
Development studies
Clinical trials
Disease and Health Conditions
Gonorrhoea
Sexually transmitted infections
Country
United Kingdom
Region
Euro area

Selected Publications

Characterisation of Neisseria gonorrhoeae strain differences in patients with multisite infection.
MIARI, VF; Blakiston, MR; Solanki, P; GUNDOGDU, O; STABLER, RA;
2024
Sexually transmitted infections
Carriage and antimicrobial susceptibility of commensal Neisseria species from the human oropharynx.
MIARI, VF; Bonnin, W; Smith, IK G; Horney, MF; Saint-Geris, SJ; STABLER, RA;
2024
Scientific reports
Ethnically diverse urban transmission networks of Neisseria gonorrhoeae without evidence of HIV serosorting.
Dave, J; Paul, J; Pasvol, TJ; Williams, A; Warburton, F; Cole, K; MIARI, VF; STABLER, R; Eyre, DW;
2019
Sexually transmitted infections
In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae.
MIARI, VF; Solanki, P; Hleba, Y; STABLER, RA; Heap, JT;
2017
Antimicrobial agents and chemotherapy
Is there a role for topical antiseptics in the treatment of gonorrhoea?
MIARI, VF; Ison, CA;
2016
Sexually transmitted infections
Accurate detection of Neisseria gonorrhoeae ciprofloxacin susceptibility directly from genital and extragenital clinical samples: towards genotype-guided antimicrobial therapy.
Pond, MJ; HALL, CL; MIARI, VF; Cole, M; Laing, KG; Jagatia, H; HARDING-ESCH, E; Monahan, IM; Planche, T; Hinds, J; Ison, CA; Chisholm, S; Butcher, PD; Sadiq, ST;
2016
The Journal of antimicrobial chemotherapy
Evaluation of non-extracted genital swabs for real-time HSV PCR.
MIARI, VF; Wall, GR; Clark, DA;
2014
Journal of medical virology
Is gonorrhea becoming untreatable?
Blomquist, PB; MIARI, VF; Biddulph, JP; Charalambous, BM;
2014
Future microbiology
Minimum inhibitory concentrations of extended spectrum cephalosporins: A systematic review and meta-analysis of Neisseria gonorrhoeae treatment failure
MIARI, VF; Mosoff, JM; CHICO, RM;
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