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Dr Isaac Osei

Research Fellow

United Kingdom

I trained as a clinician in Ghana at Kwame Nkrumah University of Science and Technology and completed an MSc in Epidemiology at the London School of Hygiene and Tropical Medicine (LSHTM) in 2015. Before enrolling at the School, I worked with the Navrongo Health Research Centre in Northern Ghana as a coordinator on research related to infectious diseases, including meningitis and malaria. I then joined the Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR) and served as the Scientific Officer for the African Research Network on Neglected Tropical Diseases (ARNTD) and the Severe Typhoid in Africa Program (SETA) coordinator. In 2019, I joined LSHTM as a Research Fellow. Currently, I serve as a Clinical Trial Epidemiologist at the Medical Research Council Unit in The Gambia at LSHTM, coordinating a series of studies that compare a reduced dose pneumococcal conjugate vaccine (PCV) schedule with the standard schedule.

Affiliations

MRC Unit The Gambia at LSHTM

Teaching

I am a member of the team responsible for administering the LSHTM distance learning program focused on Epidemiology and Control of Infectious Diseases, which includes the assessment of examinations and assignments

Research

My research interest is in infectious diseases and vaccine-related research, including pneumonia, meningitis and malaria. I am interested in studying how infectious diseases spread within populations, identifying factors contributing to their transmission, and developing strategies to prevent and control outbreaks at a population level. I am currently investigating the relationship between pneumococcal carriage and interpersonal contact patterns and its role in persistent vaccine-type pneumococcal carriage in high-transmission settings.

Research Area
Clinical research
Vaccinology
Clinical trials
Field epidemiology
Disease and Health Conditions
Pneumonia
Respiratory diseases
Meningitis
Malaria
Neglected Tropical Diseases (NTDs)
Country
Ghana
Gambia
Region
Sub-Saharan Africa (all income levels)

Selected Publications

Social contacts and mixing patterns in rural Gambia.
OSEI, I; Mendy, E; VAN ZANDVOORT, K; Young, B; Jobe, O; Sarwar, G; Mohammed, NI; BRUCE, J; GREENWOOD, B; FLASCHE, S; MACKENZIE, GA;
2025
BMC infectious diseases
Blood culture time to positivity in pediatric patients with bloodstream infection in rural Gambia.
OSEI, I; Wutor, BM; Kuyateh, A; Barjo, O; Sarwar, G; Omotosho, M; Adefila, WO; Olawale, YA; Lamin, KM; Hossain, I; Lobga, BG; Wally, M; Cham, M; Molfa, M; Salaudeen, R; MACKENZIE, GA;
2025
IJID regions
Immunogenicity of yellow fever vaccine co-administered with 13-valent pneumococcal conjugate vaccine in rural Gambia: A cluster-randomised trial.
OSEI, I; Schmidt-Chanasit, J; Licciardi, PV; Secka, O; D'ALESSANDRO, U; Salaudeen, R; Sarwar, G; CLARKE, E; Mohammed, NI; Nguyen, C; GREENWOOD, B; Jansen, S; MACKENZIE, GA;
2025
Vaccine
Standardized study performance, quality assurance, and quality control in a cluster-randomized trial: the Pneumococcal Vaccine Schedules trial.
OSEI, I; Young, B; Sarwar, G; Olatunji, YA; Hossain, I; Lobga, BG; Wutor, BM; Adefila, W; Mendy, E; Adeshola, B; Isa, YS; Olawale, YA; Lamin, KM; Nyimanta, E; Baldeh, B; Nyassi, A; Drammeh, MM; Ousman, B; Molfa, M; Salaudeen, R; MACKENZIE, GA;
2024
Trials
Factors influencing the intention of doctors to emigrate: a cross-sectional study of Ghanaian doctors.
Wutor, BM; Sarfo, FN; Nkrumah, LA; Bakuoru, LD; Amanze, CN; OSEI, I;
2024
BMC health services research
High Residual Nasopharyngeal Carriage of Vaccine Serotype Pneumococci After 12 Years of Introduction of Pneumococcal Conjugate Vaccine in The Gambia
OSEI, I; Emmanuel, M; Usuf, E; Bottomley, C; Salaudeen, R; Badji, H; Ikumapayi, N; Hill, P; Greenwood, B; Mackenzie, G;
2024
2024 Annual Meeting of American Society of Tropical Medicine & Hygiene
Gambia_Main Contact Survey
OSEI, I;
2024
Zenodo
Directly observed social contact patterns among school children in rural Gambia.
OSEI, I; Mendy, E; VAN ZANDVOORT, K; Jobe, O; Sarwar, G; WUTOR, BM; FLASCHE, S; Mohammed, NI; BRUCE, J; GREENWOOD, B; MACKENZIE, GA;
2024
Epidemics
Standardized study performance, quality assurance, and quality control in a cluster-randomized trial: The Pneumococcal Vaccine Schedules Trial
OSEI, I; Young, B; Sarwar, G; Olatunji, Y; Hossain, I; Lobga, B; WUTOR, B; Adefila, W; Mendy, E; Adeshola, B; Isa, YS; Olawale, Y; Lamin, K; Nyimanta, E; Baldeh, B; Nyassi, A; Drammeh, M; Ousman, B; Molfa, M; Salaudeen, R; Mackenzie, G;
2024
Research Square
Social contact data for the BHDSS and FWHDSS in the Gambia (2022)
OSEI, I; Mendy, E; VAN ZANDVOORT, K; Jobe, O; Sarwar, MG; MOHAMMED, N; Bruce, J; GREENWOOD, B; MACKENZIE, GA;
2024
Zenodo
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