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Dr Anna Schultze

Assistant Professor

United Kingdom

Jump to: Affiliations Teaching Research Publications
I am a pharmacoepidemiologist based in the Electronic Health Records (EHR) group researching drug and vaccine safety using large observational databases. Before joining LSHTM, I worked as an epidemiologist in the pharmaceutical industry where I led post-authorisation safety and comparative effectiveness studies, primarily using nationwide Scandinavian health registries. I completed a PhD in epidemiology at UCL in 2017, focusing on HIV drug resistance, and also hold an MSc in Epidemiology from LSHTM and a BSc in Human Sciences from UCL.

Affiliations
Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Teaching
I am a module organiser for Extended Epidemiology, and teach on Basic Epidemiology, the Professional Certificate course in Pharmacoepidemiology and Introduction to Health Data Science. My teaching covers a range of topics ranging from introductory epidemiology to reproducible programming/git. I also supervise a number of MSc students.

Research
I am broadly interested in how we can better use routinely collected data to study the effectiveness and safety of medications. My current research focuses on self-controlled study designs, specifically applied to COVID-19 vaccine safety and single-arm studies (long-term extensions of clinical trials). I have been involved in several broader studies of drug repurposing for COVID-19 and descriptive epidemiology using the OpenSAFELY platform. I'm particularly interested in reproducibility and open science, and also lead some meta-research on these practices in pharmacoepidemiology.
Research Area
Pharmacoepidemiology
Vaccines
Pharmacovigilance
Statistical methods
Research methodology

Selected Publications
Cardiorenal effects of dual blockade with Angiotensin-converting enzyme inhibitors and Angiotensin receptor blockers in people with CKD: analysis of routinely collected data with emulation of a reference trial (ONTARGET)
Baptiste, PJ; Wong, AY S; SCHULTZE, A; Clase, CM; Leyrat, C; WILLIAMSON, E; Powell, E; Mann, JF E; Cunnington, M; Teo, K; Bangdiwala, SI; Gao, P; WING, K; TOMLINSON, L;
2024
Cold Spring Harbor Laboratory
OpenSAFELY: A platform for analysing electronic health records designed for reproducible research.
Nab, L; Schaffer, AL; Hulme, W; DeVito, NJ; Dillingham, I; Wiedemann, M; Andrews, CD; Curtis, H; Fisher, L; Green, A; Massey, J; Walters, CE; Higgins, R; Cunningham, C; Morley, J; Mehrkar, A; Hart, L; Davy, S; Evans, D; Hickman, G; Inglesby, P; Morton, CE; Smith, RM; Ward, T; O'Dwyer, T; ... GOLDACRE, B.
2024
Pharmacoepidemiology and drug safety
Clinical coding of long COVID in primary care 2020-2023 in a cohort of 19 million adults: an OpenSAFELY analysis.
Henderson, AD; Butler-Cole, BF; Tazare, J; Tomlinson, LA; MARKS, M; JIT, M; BRIGGS, A; Lin, L-Y; CARLILE, O; Bates, C; Parry, J; Bacon, SC; Dillingham, I; Dennison, WA; COSTELLO, RE; Wei, Y; Walker, AJ; Hulme, W; GOLDACRE, B; Mehrkar, A; MacKenna, B; OpenSAFELY Collaborative,; HERRETT, E; EGGO, RM;
2024
EClinicalMedicine
Impact of long COVID on health-related quality-of-life: an OpenSAFELY population cohort study using patient-reported outcome measures (OpenPROMPT).
CARLILE, O; BRIGGS, A; Henderson, AD; Butler-Cole, BF C; Tazare, J; TOMLINSON, LA; MARKS, M; JIT, M; Lin, L-Y; Bates, C; Parry, J; Bacon, SC J; Dillingham, I; Dennison, WA; COSTELLO, RE; Walker, AJ; Hulme, W; GOLDACRE, B; Mehrkar, A; MacKenna, B; OpenSAFELY Collaborative,; HERRETT, E; EGGO, RM;
2024
The Lancet Regional Health - Europe
A comparison of four self-controlled study designs in an analysis of COVID-19 vaccines and myocarditis using five European databases.
SCHULTZE, A; Martin, I; Messina, D; Bots, S; Belitser, S; José Carreras-Martínez, J; Correcher-Martinez, E; Urchueguía-Fornes, A; Martín-Pérez, M; García-Poza, P; Villalobos, F; Pallejà-Millán, M; Alberto Bissacco, C; Segundo, E; Souverein, P; Riefolo, F; Durán, CE; Gini, R; Sturkenboom, M; Klungel, O; DOUGLAS, I;
2024
Vaccine
VAC4EU/CVM: WP4 SCCS sensitivity code for publication/Zenodo
Messina, D; Paoletti, O; Belitser, S; Gini, RM; Limoncella, G; SCHULTZE, A;
2024
Zenodo
ehr-lshtm/code-sharing: preprint
SCHULTZE, A; TAZARE, J;
2024
Zenodo
The role of programming code sharing in improving the transparency of medical research.
SCHULTZE, A; Tazare, J;
2023
BMJ (Clinical research ed.)
Rapid Safety Assessment of SARS-CoV-2 Vaccines in EU Member States using Electronic Health Care Data Sources (COVID Vaccine Monitor-CVM study): Final Study Report for WP3 (electronic health record data)
Durán, CE; Messina, D; Gini, R; Riefolo, F; Aragón, M; Belitser, S; Bissacco, CA; Bots, SH; De Burgos, A; Carreras-Martínez, JJ; Correcher-Martínez, E; DOUGLAS, IJ; Garcia-Poza, P; Girardi, A; Herings, R; Hoxhaj, V; Huerta, C; Hyeraci, G; Ientile, V; Ingrasciotta, Y; Limoncella, G; Lupattelli, A; Maglanoc, L; Martin, I; Martin, M; ... Sturkenboom, M.
2023
Zenodo
Association between living with children, vaccination, and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England during 2021–22
COWLING, TE; Forbes, H; Wing, K; TAZARE, J; SCHULTZE, A; Morton, CE; Bacon, S; MacKenna, B; Walker, AJ; Hulme, W; Bates, C; Mehrkar, A; Curtis, HJ; Evans, D; Inglesby, P; Davy, S; Cockburn, J; Parry, J; Hester, F; Harper, S; Douglas, IJ; EVANS, SJ W; BHASKARAN, K; WILLIAMSON, EJ; EGGO, RM; ... TOMLINSON, LA.
2023
Wellcome Open Research
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Anna Schultze

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United Kingdom