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Dr Martin Taylor

Associate Professor

United Kingdom

Jump to: Affiliations Research Publications

Affiliations
Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Antimicrobial Resistance Centre

Research
Research Area
Drug discovery and development
Drug resistance
Innate immunity
Parasites
Protozoa
Trypanosomes
Vaccines
Biochemistry
Cell biology
Genetics
Genomics
Immunology
Microbiology
Molecular biology
Parasitology
Vaccinology
Disease and Health Conditions
African trypanosomiasis
Chagas Disease
Leishmaniasis
Neglected Tropical Diseases (NTDs)
Tropical diseases

Selected Publications
Incomplete Recruitment of Protective T Cells Is Associated with Trypanosoma cruzi Persistence in the Mouse Colon.
Ward, AI; LEWIS, MD; TAYLOR, MC; KELLY, JM;
2021
Infection and Immunity
Local association of Trypanosoma cruzi chronic infection foci and enteric neuropathic lesions at the tissue micro-domain scale.
KHAN, AA; Langston, HC; Costa, FC; Olmo, F; TAYLOR, MC; McCann, CJ; KELLY, JM; LEWIS, MD;
2021
PLoS pathogens
Trypanosoma cruzi amastigotes that persist in the colon during chronic stage murine infections have a reduced replication rate.
Ward, AI; Olmo, F; ATHERTON, RL; TAYLOR, MC; KELLY, JM;
2020
OPEN BIOLOGY
Bioluminescent:Fluorescent Trypanosoma cruzi Reporter Strains as Tools for Exploring Chagas Disease Pathogenesis and Drug Activity.
TAYLOR, MC; Ward, AI; Olmo, F; FRANCISCO, AF; Jayawardhana, S; Costa, FC; LEWIS, MD; KELLY, JM;
2020
Current pharmaceutical design
Intracellular DNA replication and differentiation of Trypanosoma cruzi is asynchronous within individual host cells in vivo at all stages of infection.
TAYLOR, MC; Ward, A; Olmo, F; Jayawardhana, S; FRANCISCO, AF; LEWIS, MD; KELLY, JM;
2020
PLoS neglected tropical diseases
A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.
Macleod, OJ S; Bart, J-M; MacGregor, P; Peacock, L; Savill, NJ; Hester, S; Ravel, S; Sunter, JD; Trevor, C; Rust, S; Vaughan, TJ; Minter, R; Mohammed, S; Gibson, W; TAYLOR, MC; Higgins, MK; Carrington, M;
2020
Nature communications
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.
MacGregor, P; Gonzalez-Munoz, AL; Jobe, F; TAYLOR, MC; Rust, S; Sandercock, AM; Macleod, OJ S; Van Bocxlaer, K; FRANCISCO, AF; D'Hooge, F; Tiberghien, A; Barry, CS; Howard, P; Higgins, MK; Vaughan, TJ; Minter, R; Carrington, M;
2019
PLoS neglected tropical diseases
Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping.
Costa, FC; FRANCISCO, AF; JAYAWARDHANA, S; Calderano, SG; LEWIS, MD; Olmo, F; Beneke, T; Gluenz, E; Sunter, J; Dean, S; KELLY, JM; TAYLOR, MC;
2018
PLoS neglected tropical diseases
Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy.
LEWIS, MD; FRANCISCO, AF; TAYLOR, MC; JAYAWARDHANA, S; KELLY, JM;
2016
Cellular microbiology
The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence.
TAYLOR, MC; LEWIS, MD; FORTES FRANCISCO, A; Wilkinson, SR; KELLY, JM;
2015
PLoS neglected tropical diseases
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Martin Taylor

Contact

United Kingdom