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Prof Charlotte Warren-Gash

Clin Prof of Epi & Health Data Science

United Kingdom

I am a Professor of Epidemiology and honorary consultant in Public Health Medicine. My research uses large health datasets to investigate causes of disease in older age to inform prevention strategies. I am currently supported by a Wellcome Career Development Award focussed on understanding relationships between infections and brain health as well as through research grants from Open Philanthropy. I lead the Brain Health Group at LSHTM.

I originally qualified in medicine from Edinburgh University and trained in internal medicine in Edinburgh and London hospitals before specialising in public health. I completed an MSc in epidemiology at LSHTM in 2007. My MRC-funded PhD, awarded by UCL in 2013, investigated the role of influenza as a trigger for acute cardiovascular events. After post-doctoral experience as an NIHR clinical lecturer at the UCL Institute of Health Informatics, I joined LSHTM on a Wellcome Intermediate Clinical Fellowship in 2016.

Affiliations

Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Teaching

I am an Educational Supervisor for the UK Faculty of Public Health training scheme. I am also Deputy Chair of the exam board for the professional certificate in pharmacoepidemiology & pharmacovigilance. I teach on various MSc modules including Extended Epidemiology, Study Design and Advanced Research Methods as well as short courses including Systematic Reviews and meta-analysis. I supervise MSc summer projects and PhD students, with a particular interest in projects related to brain health.

Research

My research seeks to understand causes of disease in older age with a focus on how infections interact with other health conditions. I lead a programme of research funded by a Wellcome Career Development Award which aims to investigate relationships between infections and key components of brain health (mental health, cognitive health and sensorimotor function) in older age. This uses large, longitudinal datasets from across populations along with robust causal inference methods. Through generating new insights into the infection-brain health relationship across and within different populations, my research aims to inform the design of interventions to improve brain health worldwide.

I am also leading a large collaborative project funded by Open Philanthropy to enhance the UK Biobank dataset with additional infectious disease data to enable research into infections and non-communicable disease links.

My other research interests include social and environmental influences on health, health inequalities, vaccine epidemiology and phenotyping methods.
Research Area
Ageing
Electronic health records
Older people's health
Public health
Systematic reviews
Epidemiology
Medicine
Virology
Health inequalities
Disease and Health Conditions
Herpesviruses
Influenza
Pandemic diseases
Stroke
Infectious diseases
Neurological diseases
Cardiovascular diseases
Dementia, incl. Alzheimer's
Mental health

Selected Publications

Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data.
FORBES, H; DOUGLAS, I; Finn, A; Breuer, J; BHASKARAN, K; SMEETH, L; Packer, S; LANGAN, SM; MANSFIELD, KE; Marlow, R; Whitaker, H; WARREN-GASH, C;
2020
BMJ-BRITISH MEDICAL JOURNAL
Human herpesvirus infections and dementia or mild cognitive impairment: a systematic review and meta-analysis.
WARREN-GASH, C; FORBES, HJ; WILLIAMSON, E; Breuer, J; Hayward, AC; Mavrodaris, A; Ridha, BH; Rossor, MN; Thomas, SL; SMEETH, L;
2019
Scientific reports
Potential interactions between digoxin and direct oral anticoagulants: application of cohort & novel case-crossover designs.
WONG, AY; WARREN-GASH, C; BHASKARAN, K; LEYRAT, C; Banerjee, A; SMEETH, L; DOUGLAS, IJ;
2025
Journal of clinical epidemiology
Potential interactions between antimicrobials and direct oral anticoagulants: Population-based cohort and case-crossover study.
WONG, AY S; WARREN-GASH, C; BHASKARAN, K; LEYRAT, C; Banerjee, A; SMEETH, L; Douglas, IJ;
2025
Heart rhythm
Psoriasis and dementia: A population-based matched cohort study of adults in England.
MATTHEWMAN, J; Mansfield, KE; CADOGAN, SL; Abuabara, K; Smith, C; BHASKARAN, K; LANGAN, SM; WARREN-GASH, C;
2025
Annals of clinical and translational neurology
Potential interactions between direct oral anticoagulants and atorvastatin/simvastatin: cohort and case-crossover study.
WONG, AY; WARREN-GASH, C; BHASKARAN, K; LEYRAT, C; Banerjee, A; Smeeth, L; Douglas, I;
2024
The British journal of general practice : the journal of the Royal College of General Practitioners
Trends and variation in issuance of high-cost narcolepsy drugs by NHS England organisations and regions from 2019 to 2022.
Van Someren, F; Wiedemann, M; WARREN-GASH, C; SYKOROVA, M; Mistry, H; Miller, MA; Leschziner, G; NOLTE, E; BELOT, A; Smith, IE; Quinnell, T; Eriksson, SH; STRONGMAN, H;
2024
Journal of sleep research
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