Gwen's research focuses on the dynamics of antibiotic resistance. Her main focus is her fellowship topic, which aims to explore the interaction between age, gender and the dynamics of antimicrobial resistance. Alongside this, her research falls broadly into three areas: understanding the dynamics of bacteriophage driven resistance evolution in S. aureus, modelling One Health interventions and data exploration within SEFASI (the JPIAMR project she is PI of) and developing better methods to support data-guided empiric antibiotic guidelines.

During the COVID-19 pandemic, Gwen was involved in work to estimate the burden of hospital-acquired infection and settings of transmission, as well as the interaction of COVID-19 with AMR drivers.

At the HPRU in HCAI and AMR at Imperial College London Gwen worked on projects using locally collected data to design better interventions for control of carbapenem resistant Enterobacteriaceae alongside thinking about the fundamental question of where does AMR originate from?

Gwen has a long standing interest in Mycobacterium tuberculosis, specifically the resistant subpopulation (multidrug resistant, MDR-TB). Gwen has been involved in investigating new methods to control the spread (e.g. antiretroviral therapy, potential new TB vaccines) as well as the impact of shortening therapy.