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Dr Max Eyre

Assistant Professor

United Kingdom

I am an Assistant Professor in the Environmental Health Group with a background in epidemiology and spatial statistics. My research investigates how the environment, climate and WASH provision affect the transmission of a range of infectious diseases, with a focus on complex urban settings.

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Teaching

At LSHTM, I am the module organiser for the Environmental Epidemiology module and lecture on the Introduction to Disease Agents and their Control module for the Control of Infectious Diseases MSc, on WASH for the Diploma in Tropical Medicine & Hygiene (DTMH) and also on the Design and Analysis of Epidemiological Studies module. I am a tutor for the Control of Infectious Diseases MSc and on the distance-learning module Control of Infectious Diseases.

 

I currently supervise/co-supervise three PhD students based at LSHTM, Lancaster University and the Federal University of Bahia.

 

I regularly supervise MSc research projects - any interested students please feel free to contact me.

Research

My research primarily focusses on studying transmission mechanisms of infectious diseases, with a focus on climate-sensitive pathogens, using spatial statistical models and data collected via community-based studies and administrative health data. I am co-lead for the 'Improving Environmental and Planetary Health' challenge at the LSHTM Centre for Data and Statistical Science for Health (DASH).

 

I am currently undertaking an RGHI-funded fellowship exploring the link between environmental hygiene, flooding and health for three climate-sensitive environmental and zoonotic diseases (EZDs) in marginalised urban communities in Salvador, Brazil using a One Health approach. The project aims to address a critical evidence gap on the impact of WASH interventions (simplified sewerage with community participation and health education) on EZD transmission. In this three-year longitudinal study we use an eco-epidemiological approach to delineate the mechanisms and complex interactions between animal reservoirs, the environment, climate and human behaviour that drive transmission of these diseases. This study is a collaboration with the Federal University of Bahia and Fiocruz in Salvador, Brazil.

 

I am co-I on another study 'Examining the relationships between domestic hygiene, a simplified sewerage intervention, and enteric pathogen exposure'. In this study we are examining how hygiene behaviours influence the impact of sanitation on enteric pathogen exposure. The study is nested within an existing trial of a simplified sewerage intervention in low-income, informal neighbourhoods of Salvador, Brazil, which I also collaborate on.

 

I also develop and apply geostatistical models for disease prevalence mapping to inform policy for preventive chemotherapy control for schistosomiasis, soil-transmitted helminths and other NTDs for country MOHs in West, Central and East Africa.

 

Much of my other work has focussed on leptospirosis and arboviruses in complex urban settings. This includes a collaboration with the Federal University of Bahia and the University of Bristol to develop and validate a hydro-epidemiological model for Leptospira pathogen transportation and accumulation in the environment.

 

I am currently also investigating the effect of climate and environment on WASH intervention effectiveness using observational and trial data and using causal inference approaches to understand how climate vulnerability and flooding drive zoonotic disease burden.

Research Area
GIS/Spatial analysis
Statistical methods
Epidemiology
Disease control
Environmental hygiene
Environmental health
Climate change
Complex interventions
Sanitation
Hygiene
Modelling
Protozoa
Bacteria
Social and structural determinants of health
Disease and Health Conditions
Leptospirosis
Toxoplasmosis
Dengue
Soil transmitted helminths
Neglected Tropical Diseases (NTDs)
Zoonoses
Vector borne diseases
Infectious diseases
Country
Brazil
United Kingdom
Region
Latin America & Caribbean (all income levels)

Selected Publications

Linking rattiness, geography and environmental degradation to spillover <i>Leptospira</i> infections in marginalised urban settings: An eco-epidemiological community-based cohort study in Brazil.
EYRE, MT; Souza, FN; Carvalho-Pereira, TS A; Nery, N; De Oliveira, D; Cruz, JS; Sacramento, GA; Khalil, H; Wunder, EA; Hacker, KP; Hagan, JE; Childs, JE; Reis, MG; Begon, M; Diggle, PJ; Ko, AI; Giorgi, E; Costa, F;
2022
eLife
SARS-CoV-2 antibodies and breakthrough infections in the Virus Watch cohort.
Aldridge, RW; Yavlinsky, A; Nguyen, V; EYRE, MT; Shrotri, M; Navaratnam, AM D; Beale, S; Braithwaite, I; Byrne, T; Kovar, J; FRAGASZY, E; Fong, WL E; Geismar, C; Patel, P; Rodger, A; Johnson, AM; Hayward, A;
2022
Nature Communications
Effect of Sewerage on the Contamination of Soil with Pathogenic Leptospira in Urban Slums.
Casanovas-Massana, A; Neves Souza, F; Curry, M; De Oliveira, D; De Oliveira, AS; EYRE, MT; Santiago, D; Aguiar Santos, M; Serra, RM R; Lopes, E; Xavier, BI; Diggle, PJ; Wunder, EA; Reis, MG; Ko, AI; Costa, F;
2021
Environmental science & technology
Poverty, sanitation, and Leptospira transmission pathways in residents from four Brazilian slums.
Khalil, H; Santana, R; De Oliveira, D; Palma, F; Lustosa, R; EYRE, MT; Carvalho-Pereira, T; Reis, MG; Ko, AI; Diggle, PJ; Alzate Lopez, Y; Begon, M; Costa, F;
2021
PLoS neglected tropical diseases
Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study.
EYRE, MT; Burns, R; Kirkby, V; Smith, C; Denaxas, S; Nguyen, V; Hayward, A; Shallcross, L; FRAGASZY, E; Aldridge, RW;
2021
Wellcome open research
COVID-19 among people experiencing homelessness in England: a modelling study.
Lewer, D; Braithwaite, I; Bullock, M; EYRE, MT; White, PJ; Aldridge, RW; Story, A; Hayward, AC;
2020
The Lancet. Respiratory medicine
A multivariate geostatistical framework for combining multiple indices of abundance for disease vectors and reservoirs: a case study of <i>rattiness</i> in a low-income urban Brazilian community.
EYRE, MT; Carvalho-Pereira, TS A; Souza, FN; Khalil, H; Hacker, KP; Serrano, S; Taylor, JP; Reis, MG; Ko, AI; Begon, M; Diggle, PJ; Costa, F; Giorgi, E;
2020
Journal of the Royal Society, Interface
Piloting an integrated approach for estimation of environmental risk of Schistosoma haematobium infections in pre-school-aged children and their mothers at Barombi Kotto, Cameroon.
EYRE, MT; Stanton, MC; Macklin, G; Bartoníček, Z; O'Halloran, L; Eloundou Ombede, DR; Chuinteu, GD; Stewart, M; LaCourse, EJ; Tchuem Tchuenté, LA; Stothard, JR;
2020
Acta tropica
Disentangling the influence of reservoir abundance and pathogen shedding on zoonotic spillover of the &lt;i&gt;Leptospira&lt;/i&gt; agent in urban informal settlements.
Soni, N; EYRE, MT; Souza, FN; Diggle, PJ; Ko, AI; Begon, M; Pickup, R; Childs, JE; Khalil, H; Carvalho-Pereira, TS A; Pertile, AC; Carvalho, M; De Oliveira, D; Nery, N; Giorgi, E; Costa, F;
2024
Frontiers in public health
Gender differences in the perception of leptospirosis severity, behaviours, and Leptospira exposure risk in urban Brazil: a cross-sectional study.
Delight, EA; De Carvalho Santiago, DC; Palma, FA G; De Oliveira, D; Souza, FN; Santana, JO; HIDANO, A; López, YA A; Reis, MG G; Ko, AI; MARPHATIA, AA; Cremonense, C; Costa, F; EYRE, MT;
2024
medRxiv
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