Dr Daniela Manno
Clinical Assistant Professor
London School of Hygiene & Tropical Medicine
Keppel Street
London
WC1E 7HT
United Kingdom
I am a clinical epidemiologist with extensive expertise in infectious diseases and clinical trials, particularly in the field of vaccine research for outbreak-prone infectious diseases. My PhD work, which involved assessing the safety and immunogenicity of the Ad26.ZEBOV and MVA-BN-Filo vaccine regimen against Ebola virus disease (EVD) in Sierra Leone, provided me with critical insights into the complexities of vaccine research for emerging infections.
Additionally, I served as the responsible physician for the London School of Hygiene & Tropical Medicine (LSHTM) during a large-scale vaccine trial in the Democratic Republic of Congo (DRC) that administered the Ad26.ZEBOV and MVA-BN-Filo regimen to over 20,000 adults and children, including pregnant women, during the 2018-2020 EVD outbreak in North Kivu and Ituri provinces. I also coordinated a follow-up study on participants vaccinated with the same vaccine regimen in Sierra Leone (NCT03820739) and, as a co-principal investigator at LSHTM, led a safety follow-up study with a similar cohort in Tanzania, securing funding of €145,967 (NCT02661464).
My current interests focus on improving the inclusion of pregnant and breastfeeding women in vaccine research for emerging infections to enhance the safety of these women and their babies during health emergencies. Additionally, I am involved in projects investigating Lassa fever epidemiology in Sierra Leone and summarising the evidence on the effectiveness of single-dose vaccination for Human Papilloma Virus (HPV).
Affiliations
Centres
Teaching
I am a tutor and marker for the modules 'Applying Public Health Principles in Developing Countries' (3198) and ‘Control of Sexually Transmitted Infections’ (3192). Additionally, I facilitate the Decolonising Global Health (DGH) talks for the Diploma in Tropical Medicine and Hygiene (DTM&H 2024).
Research
My primary research interests centre on conducting clinical trials and other epidemiological studies in the field of infectious diseases and vaccines. Currently, I am particularly focused on improving the inclusion of pregnant and breastfeeding women in vaccine research for emerging infections, with the aim of enhancing the safety of these women and their babies during health emergencies. Additionally, I am involved in projects investigating Lassa fever epidemiology in Sierra Leone and summarising the evidence on the effectiveness of single-dose vaccination for HPV.