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Dr Caroline Minassian

Assistant Professor

United Kingdom

Jump to: Affiliations Teaching Research Publications

I am an epidemiologist working in electronic health records (EHR) research with a particular interest in maternal health. I hold a BA Hons in Experimental Psychology from Oxford University and an MSc in Epidemiology from LSHTM. My PhD, awarded in 2014, investigated the role of acute infections and inflammation in vascular events. I have many years' experience working with large databases of linked health records from primary and secondary care in the UK (CPRD and HES) and administrative claims data from the US (Medicaid and Medicare). I have published on a range of topics including inflammation and vascular disease, pregnancy, and more recently maternal thyroid disease funded by my UKRI Innovation Fellowship.

 

Affiliations
Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Teaching

I have been teaching on face-to-face and distance learning MSc modules since 2009, including STEPH, Statistical Methods in Epidemiology, Basic Epidemiology, and the Introductory Course in Epidemiology and Medical Statistics (ICEMS) short course. I have been a Module Organiser for Basic Epidemiology (2009-2013) and for the DL MSc Epidemiology Project module EPM500 (2017-2020). I currently teach on the DL Statistical Methods in Epidemiology study module EPM202.

Research

My main research focus is on maternal health and methods to optimise the identification of pregnancies in electronic health record databases. Since 2016, I have co-led a joint research collaboration between LSHTM and CPRD to develop an algorithm to identify and date pregnancies and their outcomes within the CPRD primary care database. This work established a Pregnancy Register in CPRD, a novel research tool which has been used in over thirty published studies incuding my recent work on preconception management of hyperthyroidism. I am currently interested in applying the Pregnancy Register, new linkages, and optimal methods to study the uptake and safety of vaccines recommended during pregnancy.

Research Area
Maternal health
Child health
Electronic health records
Research methodology
Immunisation
Pregnancy care management
Disease and Health Conditions
Cardiovascular diseases

Selected Publications
Identification of misclassified pregnancy episodes in women of childbearing potential exposed to drugs with known teratogenic potential in the CPRD GOLD Pregnancy Register.
Lee, C; Rizzi, S; Bierrenbach, AL; Antunes, L; Nissinen, N-M; Rocha, O; Campbell, J; MINASSIAN, C; Hodgson, S; Broe, A;
2024
Pharmacoepidemiology and drug safety
Identification of misclassified pregnancy episodes in women of childbearing potential exposed to drugs with known teratogenic potential in the CPRD GOLD Pregnancy Register
Broe, A; Lee, C; Rizzi, S; Bierrenbach, AL; Antunes, L; Nissinen, N-M; Rocha, O; Campbell, J; MINASSIAN, C; Hodgson, S;
2023
Authorea, Inc.
Identification of misclassified pregnancy episodes in women of childbearing potential exposed to drugs with known teratogenic potential in the CPRD GOLD Pregnancy Register
Broe, A; Lee, C; Rizzi, S; Bierrenbach, AL; Antunes, L; Nissinen, N-M; Rocha, O; Campbell, J; MINASSIAN, C; Hodgson, S;
2023
Authorea, Inc.
Alcohol Use and Sustained Virologic Response to Hepatitis C Virus Direct-Acting Antiviral Therapy.
Cartwright, EJ; Pierret, C; MINASSIAN, C; Esserman, DA; Tate, JP; Goetz, MB; Bhattacharya, D; Fiellin, DA; Justice, AC; Lo Re, V; RENTSCH, CT;
2023
JAMA network open
Preconception Management of Hyperthyroidism and Thyroid Status in Subsequent Pregnancy: A Population-Based Cohort Study.
MINASSIAN, C; Allen, LA; Okosieme, O; Vaidya, B; Taylor, P;
2023
The Journal of clinical endocrinology and metabolism
Supplementary material for: "Preconception management of hyperthyroidism and thyroid status in subsequent pregnancy: a population-based cohort study"
MINASSIAN, C; Allen, LA; Okosieme, O; Vaidya, B; Taylor, P;
2023
London School of Hygiene & Tropical Medicine
Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England: a descriptive cohort study within the OpenSAFELY platform.
OpenSAFELY Collaborative,; TAZARE, J; Walker, AJ; TOMLINSON, LA; Hickman, G; RENTSCH, CT; WILLIAMSON, EJ; BHASKARAN, K; Evans, D; WING, K; Mathur, R; WONG, AY; SCHULTZE, A; Bacon, S; Bates, C; Morton, CE; Curtis, HJ; Nightingale, E; McDonald, HI; Mehrkar, A; Inglesby, P; Davy, S; MacKenna, B; Cockburn, J; Hulme, WJ; ... GOLDACRE, B.
2022
Wellcome open research
Investigating the optimal handling of uncertain pregnancy episodes in the CPRD GOLD Pregnancy Register: a methodological study using UK primary care data.
Campbell, J; BHASKARAN, K; Thomas, S; Williams, R; MCDONALD, HI; MINASSIAN, C;
2022
BMJ open
Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England: a descriptive cohort study within the OpenSAFELY platform
The OpenSAFELY Collaborative,; TAZARE, J; Walker, A; TOMLINSON, L; Hickman, G; RENTSCH, C; WILLIAMSON, E; BHASKARAN, K; Evans, D; WING, K; MATHUR, R; WONG, AY S; SCHULTZE, A; Bacon, S; Bates, C; Morton, C; Curtis, H; NIGHTINGALE, E; MCDONALD, H; Mehrkar, A; Inglesby, P; Davy, S; MacKenna, B; Cockburn, J; Hulme, W; ... GOLDACRE, B.
2022
Wellcome Open Res
Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform.
WILLIAMSON, EJ; MCDONALD, HI; BHASKARAN, K; Walker, AJ; Bacon, S; Davy, S; SCHULTZE, A; TOMLINSON, L; Bates, C; Ramsay, M; Curtis, HJ; FORBES, H; WING, K; MINASSIAN, C; TAZARE, J; Morton, CE; NIGHTINGALE, E; Mehrkar, A; Evans, D; Inglesby, P; MacKenna, B; Cockburn, J; RENTSCH, CT; MATHUR, R; WONG, AY S; ... KUPER, H.
2021
BMJ (Clinical research ed.)
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Caroline Minassian

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United Kingdom