What we do

The focus of the Modelling and Economic Evaluation of Vaccines theme is to develop vaccine impact models to understand the immunological, epidemiological, and economic dynamics of vaccination, and generate evidence to inform vaccine policy and practice at the global, regional, and national levels. 

The research portfolio includes:

• Optimising vaccination strategies for control and elimination of immunizing infections
• Immune response dynamics pre- and post-vaccination
• Epidemiological and economic impact of vaccination programmes
• Global, regional, and country-specific decisions about vaccination
• Inform potential future investments and vaccine scale-up opportunities
• Impact of vaccines on antimicrobial resistance

Collaboration

Modellers here work closely with a multidisciplinary group of researchers interested in vaccines, including epidemiologists, biostatisticians, social science researchers, computer scientists, and clinicians. We welcome collaborations related to vaccine modelling, and you are welcome to directly contact the members. See full list of collaborators below.

Monthly meetings

We meet on a monthly basis, 1st Wednesday of the month at 11:30AM, and all interested are welcome to attend (subscribe to the mailing list for monthly meeting announcements). 

Members

Akira Endo
Alexis Robert
Andrew Clark
Billy Quilty
Chaelin Kim
Chu-Chang Ku
Ciara McCarthy
David Hodgson
Fiammetta Bozzani
Frank Sandmann
Han Fu
Hikaru Bolt
Hira Tanvir
Hyolim Kang
John Edmunds
Kaja Abbas
Katherine Atkins
Kathleen O'Reilly
Kevin van Zandvoort
Kiesha Prem
Marc Baguelin
Mark Jit
Megan Auzenbergs
Naomi Fuller​​​​​
Naomi Waterlow
Nicholas Davies
Palwasha Anwari 
Peixuan Zhang
Rebecca Clark
Richard White
Rosalind Eggo
Sebastian Funk
Simon Procter
Sol Kim
Stefan Flasche
Su Myat Han
Tom Sumner
Tomoka Nakamura
Yang Liu
Yung-Wai Chan

Collaborators

We are interested in new collaborations with researchers and decision-makers on epidemiological and economic analyses to inform public health decisions about vaccination in any setting.

We work closely with a multidisciplinary group of vaccine researchers, including biostatisticians, clinicians, computer scientists, epidemiologists and social scientists. 

Our collaborations include:

• Antimicrobial Resistance Centre, LSHTM
• Centre for Maternal, Adolescent, Reproductive, & Child Health, LSHTM
• Electronic Health Records Group, LSHTM
• Global Health Economics Centre, LSHTM
• Health in Humanitarian Crises Centre, LSHTM
• MRC Unit The Gambia
• Vaccine Centre, LSHTM
• Bill and Melinda Gates Foundation (BMGF)
• Epicentre MSF
• International Vaccine Institute
• The United Nations International Children's Emergency Fund (UNICEF)
• World Health Organization (WHO)
• Global Polio Eradication Initiative
• International AIDS Vaccine Initiative (IAVI)
• The Collaboration for TB Vaccine Discovery (CTVD)
• The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM)
• Modelling Economics Unit, UK Health Security Agency
• NIHR Health Protection Research Unit in Immunisation
• NIHR Health Protection Research Unit in Modelling and Health Economics
• Biocomplexity Institute, University of Virginia
• Centre for Health Economics Research and Modelling of Infectious Diseases (CHERMID), University of Antwerp
• Chinese Academy of Medical Sciences
• Christian Medical College (CMC) Vellore, India
• Health Intervention and Technology Assessment Program, Thailand
• Murdoch Children's Research Institute, Australia
• Nagasaki University, Japan
• National Institute of Infectious Diseases, Japan
• National Institutes of Health (NIH)
• Newall Lab, University of New South Wales
• Brisson Lab in Mathematical Modelling and Health Economics of Infectious Disease, University of Laval
• Robert Koch Institute, Germany
• Save the Children UK & Save the Children Somaliland
• Saw Swee Hock School of Public Health (SSHSPH), National University of Singapore
• School of Public Health, University of Hong Kong
• Shanghai Fudan University
• Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
• The National Institute for Communicable Diseases (NICD), South Africa
• Vaccine Research and Development Center, Dejima Infectious Disease Research Alliance, Nagasaki University

Projects

Chikungunya burden in endemic and epidemic settings and potential health impact of vaccination: climate-sensitive infectious disease modelling
Conducting climate-sensitive infectious disease modelling to estimate chikungunya burden and potential health impact of vaccination

Group B Streptococcus Vaccination
Evaluating impact and cost-effectiveness of maternal Group B Strep vaccines and immunization strategies worldwide.

Health and Economic Impact of Hib, Pneumococcal, Rotavirus and HPV vaccination in Sudan
Estimating the health and economic impact of Hib, Pneumococcal, Rotavirus and HPV vaccination in Sudan.

Measles-Rubella Microarray Patches initial Full Vaccine Value Assessment (MR-MAP iFVVA)
Modelling the introduction scenarios of measles-rubella microarray patches and analysing their impacts on measles burden and economic benefits.

Modelling norovirus transmission dynamics and evaluating vaccination strategies: implications for acute kidney injury epidemiology
Studying norovirus transmission dynamics and vaccinations strategies to estimate its potential impact on acute kidney injury epidemiology.

Modelling vaccination strategies for polio eradication

NIHR EPIC

Single-Dose HPV Vaccine Evaluation Consortium
Collating and synthesising existing evidence and evaluating new data on the potential for single-dose human papillomavirus (HPV) vaccine delivery.

Social contact patterns in Japan during the COVID-19 pandemic
Exploring the transmission dynamics of COVID-19 in Japan.

Strengthening capacity in China for vaccine research and decision making
Generating evidence and supporting evidence-based policy-making around the introduction of new vaccines into the national immunisation programme in China.

TB Vaccine Modelling

Vaccine Impact Modelling Consortium (VIMC)
Modelling the impact of vaccination programmes worldwide.