London School of Hygiene & Tropical Medicine

This module equips students with the essential skills needed to analyse and interpret data from cohort, case-control and cross-sectional studies. The module is assessed through an analysis of a given dataset and a reporting exercise of methods and findings.

Intended learning outcomes

Upon successful completion of the module, a student will be able to: 

• Explain the key statistical and epidemiological concepts which underlie the analysis of epidemiological data.
• Perform analyses of data arising from epidemiological studies, using appropriate computer software (the software used throughout will be Stata, though R-scripts will be made available for some practical sessions).
• Investigate and assess confounding and effect modification/interaction in epidemiological data.
• Interpret appropriately the results of these analyses, taking into account study design issues.
• Write a clear report presenting and interpreting the results of an analysis of epidemiological data.

Session Content

The module covers the following topics: 

• Cohort studies: analysis of rates using stratification to investigate confounding and interaction; Kaplan-Meier survival analysis & log-rank test; introduction to Poisson and Cox regression.
• Case-control studies: design issues including selection of controls and matching; analysis of studies using stratification to investigate confounding and interaction. 
• Likelihood theory.
• Logistic regression for the analysis of case-control, cross-sectional and fixed-length cohort studies.
• Reporting of results.

Mode of delivery

This module is delivered predominantly face-to-face. Where specific teaching methods (lectures, seminars, discussion groups) are noted in this module specification these will be delivered by predominantly face-to-face sessions. There will be a combination of live and interactive activities (synchronous learning) as well as self-directed study (asynchronous learning).

Assessment

For their summative assessment, students are asked to undertake a data analysis exercise, similar to that which they undertake towards the end of the taught component of the module. Students are provided with an epidemiological dataset and a specific research question. They are asked to analyse the dataset to address the research question and to prepare a brief report describing their analysis strategy and the results they obtained, and to discuss their results in the light of the methods used to obtain and analyse the data. 

The assessment task requires students to demonstrate: the ability to select and apply appropriate statistical methods to a specific problem, including the investigation of confounding and effect modification; the ability to present their analysis strategy and results in an appropriate way; the ability to interpret their findings appropriately in light of the study design and research question. The assessment task thus gives students an opportunity to consolidate their learning and requires students to apply their learning across the whole of the module.

Credits

• CATS: 15
• ECTS: 7.5

Module specification

For full information regarding this module please see the module specification.