OASIS, based in India, is a multi-disciplinary partnership between AMR and health systems researchers and implementors at LSHTM, the Public Health Foundation of India, iKURE TechSoft , All India Institute of Medical Sciences, Kalyani , West Bengal University of Animal and Fishery Sciences and Nuffield Department of Medicine, Oxford University.   

The OASIS solution aims to empower community based informal healthcare and antibiotic providers  for humans and animals with cutting-edge technologies to collect data on AMR at the community level. This initiative is critical in lower-income countries, where antibiotic-resistant infections disproportionately affect vulnerable populations who have limited access to formal sources of healthcare and antibiotics.  OASIS transforms rural healthcare by enabling a critical group of health workers and paravets to monitor personal antimicrobial provision data for infections treated via the Antibiotic Bandhu (friend of antibiotics) app. By integrating this with regional AMR data and facilitating systematic mentorship links with local doctors and veterinarians, the app will empower providers to adopt responsible and standardized antimicrobial practices. 

Meenakshi Gautham, Assistant Professor at LSHTM and team lead for OASIS: said, “This prestigious award affirms that our efforts are on the right track and validates our approach. We collaborate with providers who are foundational to the health system and key players within a vast informal health system. This system, with its own semi-sanctioned knowledge production pathways and supply chains, involves numerous formal and informal actors co-producing healthcare and antibiotic practices that are non-standardised. Our goal is to demonstrate that by improving access pathways to antibiotics through this system, and leveraging a multi-purpose digital solution, we can effectively address the drivers of excessive antibiotic use in both human and animal healthcare in community settings. Antibiotic stewardship in community settings must begin here.” 

The Trinity Challenge's grand prize of £1 million was awarded to Farm2Vet: Combatting AMR on the Farm Frontier, a project in Vietnam that seeks to promote responsible antibiotic use in food-producing animals. By offering farmers instant, low-cost access to veterinary services for disease diagnosis and treatment advice, Farm2Vet aims to curb the misuse of antibiotics in agriculture. The data collected through this platform will also help policymakers identify antibiotic resistance hotspots and take preventive measures. 

In addition to OASIS, the other joint second prize winner, also receiving £600,000, is AMRSense: Empowering Communities with a Proactive One Health Ecosystem. This project, also based in India, focuses on equipping community health workers in the public sector with new technologies to gather data on AMR. 

The third prize of £500,000 went to AMRoots: Grassroots AMR in Small Scale Farming Communities, based in South Africa. AMRoots will generate vital data on the development and transmission of antibiotic resistance in livestock farming communities, essential for the future food security of sub-Saharan Africa. 

All the winners will receive ongoing post-award innovation and scaling support to help implement their solutions effectively.