Theme leads

• Segun Fatumo, Associate Professor of Genetic Epidemiology & Bioinformatics
• Ozan Gundogdu, Associate Professor in Molecular Microbiology & Bioinformatics
• Alexandra Lewin, Associate Professor in Biostatistics

About

The molecular and imaging data theme seeks to engage with a range of groups working in this area, including those working on pathogen genomics and other largescale ‘omics data, pathogen and diagnostic imaging, groups focused on immunological and serological data as well as those collecting and analysing the full spectrum of pathogen related data and metadata.

There is an amazing amount of highly diverse molecular data now available from small molecule therapeutics, to protein structure, to serological/immunological markers, to diagnostic assay results, amongst many others generated from laboratory experiments, collected clinically and as part of large-scale epidemiological/population studies­. This is in addition to the availability of very large datasets of ‘omics, and in particular genomics, data which has been one of the major revolutions in biology in the past 20 years. There is also a wide variety of imaging data available from the level of the single cell all the way to the whole organism, generated from laboratory experiments and collected clinically, that relate to humans, vectors and pathogens.

LSHTM is uniquely placed to access a wide variety of such data from around the globe, which is being applied to an array of health challenges, from diagnostics and surveillance to development of new interventions and fundamental understanding of host/pathogen biology.

Areas of active research

• Genomics
  • Human genomics
  • Pathogen genomics
• Metagenomics
  • Host-pathogen dynamics
• Transcriptomics
  • Pathogen and host responses
• Imaging
  • Confocal microscopy